Results 61 to 70 of about 23,232 (259)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Preparation of Multi-Motive Grid Questionnaire for Social Networking Sites Use.

open access: yesPLoS ONE, 2020
This study draws on previous studies to develop the Social Networking Sites Use Multi-Motive Grid Questionnaire (SNSU-MMG) and test its reliability and validity.
Juan Hou   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Do highly cited clinicians get more citations when being present at social networking sites?

open access: yesJournal of Education and Health Promotion, 2018
Background and Aims: The advent of social networking sites has facilitated the dissemination of scientific research. This article aims to investigate the presence of Iranian highly cited clinicians in social networking sites.
Fatemeh Ramezani-Pakpour-Langeroudi   +2 more
doaj   +1 more source

Analysis of the Presence of Most Best-Ranked Universities on Social Networking Sites

open access: yesInformatics, 2020
Universities are becoming aware of the importance of social networking sites for the reinforcement of their institutional brands. This study was conducted to analyze the extent to which best-ranked universities use social networking sites. A quantitative
Gabriel Valerio-Ureña   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Relationship between Social Networking and Physical Activity of DPT Students of Riphah College of Rehabilitation Sciences Rawalpindi

open access: yesJournal Riphah College of Rehabilitation Sciences, 2018
Background: This study investigates how physical active students are and what is the effect of social networking on their physical activity.
Shafaq Shahid   +3 more
doaj  

A Blockchain Enhanced Framework for Social Networking

open access: yesLedger, 2019
Social networking sites have given users unprecedented opportunities for the generation and dissemination of content. A variety of social networking sites exist for different purposes, to afford users a range of anonymous and non-anonymous options for ...
Renita M Murimi
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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