Results 141 to 150 of about 490,883 (317)
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla+15 more
wiley +1 more source
The Triad: Organizational Cultural Values, Practices and Strong Social Intra-Firm Networks
Faiza Khoja
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Book Reviews: Networks : John Scott: Network Analysis: A Handbook. London, England, and New bury Park, CA: Sage Publications, 1992. Stanley Wasserman and Katherine Faust: Social Network Analysis: Methods and Applications. Cambridge, England and New York: Cambridge University Press, 1994 [PDF]
Blyden B. Potts
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This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert+13 more
wiley +1 more source
The X-Club. A social network of science in late-Victorian England
Roy MacLeod
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Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf+10 more
wiley +1 more source
The Statistical Analysis of Local Structure in Social Networks
Paul W. Holland, Samuel Leinhardt
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This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker+16 more
wiley +1 more source