Results 181 to 190 of about 60,902 (257)

Advancing Understanding of Subjective Liveability for People With Disability

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Modern liveability frameworks aim to enhance health and well‐being through equity‐based measures across built, natural, social, and economic environments, yet they often overlook the perspectives of people with disability. This study explored expectations of liveable neighbourhoods among adults with diverse disability experiences in urban and ...
Maria Hobbs   +3 more
wiley   +1 more source

Genome‐wide network analysis identifies the lncRNA‐92467/miR‐205‐5p/PTPRM/CAMs axis in a rat model of hypoxic pulmonary hypertension

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The pathogenesis of hypoxic pulmonary hypertension (HPH) remains unclear. In this study, we explored its key regulatory mechanisms using animal models, RNA sequencing, and cellular assays. We found that lncRNA‐92467 functions as a ceRNA, binding miR‐205‐5p, and thereby upregulating PTPRM, inhibiting abnormal proliferation and migration of endothelial ...
Yan‐Ying Shen   +7 more
wiley   +1 more source

ABCA1 deficiency‐induced cholesterol accumulation aggravates colonic epithelial injury in knockout hamsters

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We established ABCA1‐knockout Syrian golden hamsters as a novel and physiologically relevant model for colitis research. When challenged with a high‐fat diet, ABCA1‐deficient hamsters developed exacerbated colonic inflammation and impaired mucosal barrier integrity, driven by intracellular cholesterol accumulation.
Chang Liu   +10 more
wiley   +1 more source

Animal models of anemia of inflammation: Methodological advances, limitations, and translational applications

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Anemia of inflammation is a highly prevalent secondary anemia complicating chronic inflammatory diseases. Current animal models are categorized into sterile inflammation, disease‐specific, and genetically engineered models, with comparative analysis of their modeling principles, characteristic phenotypes, and translational advantages to elucidate core ...
Jiayi Cheng   +4 more
wiley   +1 more source

Evaluation and Optimization of COD Removal Performance for a Domestic Wastewater Treatment Plant by Response Surface Methodology: The Case of Van Muradiye

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT In this study, the performance of the Van Muradiye Domestic Wastewater Treatment Plant was evaluated with Response Surface Methodology (RSM). The effects of pH, conductivity, dissolved oxygen (DO), and suspended solids (SS) on the chemical oxygen demand (COD) removal efficiency were evaluated using samples collected from the plant's inlet and ...
Emine Cangül   +2 more
wiley   +1 more source

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