Results 141 to 150 of about 161,335 (219)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Editorial: Linking knowledge across borders: science diasporas and global south development. [PDF]

Front Res Metr Anal
Echeverría-King LF, Bonilla K, Pantović B, Bámaca-López E, Carneiro AM, Buyuktanir Karacan D.   +5 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Americans' multidimensional relationship with science: Is citizen science a path forward? [PDF]

PLoS One
Joyner BN, Larson LR, Cooper CB, Busch KC, Johnson C.   +4 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Life Satisfaction and Psychological Distress in Relation to Mediterranean Lifestyle Adherence and Behavioural Correlates: Findings from the MEDIET4ALL International Survey. [PDF]

Nutrients
Ammar A, Salem A, Trabelsi K, Montalvan M, Bouaziz B, Boujelbane MA, Kerkeni M, Masmoudi L, Ghazzawi HA, Amawi AT, Orhan BE, Zambrano-Villacres R, Heydenreich J, Schallhorn C, Driss T, Frias-Toral E, Zmijewski P, Jahrami H, Husain W, Grosso G, Chtourou H, Schöllhorn WI.   +21 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Children with Disabilities and Chronic Diseases: Perspectives, Challenges, and Opportunities: A Guest Editorial for the Article Collection. [PDF]

J Multidiscip Healthc
Abuhammad S.
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Types of Exercise and Risk of Developing Dementia in Older Japanese Community-Dwelling Adults: A Prospective Study. [PDF]

Geriatr Gerontol Int
Nagata K, Tsunoda K, Fujii Y, Seol J, Jindo T, Shibuya K, Okura T.   +6 more
europepmc   +1 more source