Results 71 to 80 of about 161,335 (219)

From the perception of science to the design of teaching materials [PDF]

open access: yesJCOM: Journal of Science Communication, 2007
To design teaching materials starting from the subject matter in Science field, from the contents of textbooks or by studying the syllabuses are regular practices within schools. The SEDEC project proposes concrete and innovative modalities of conceiving
Laura Dumbrăveanu
doaj  

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

What is a scientist’s job? From the drawings to the citizenship (French ofiginal version) [PDF]

open access: yesJCOM: Journal of Science Communication, 2007
IUFM is a centre for the in-service training of teachers and the development of didactic research. IUFM contribution to the SEDEC project is essentially built on a reflexion on educational implications of the links between science and European ...
Etienne Bolmont
doaj  

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Science popularization and European citizenship in Poland (Polish original version) [PDF]

open access: yesJCOM: Journal of Science Communication, 2007
The idea to link European citizenship and science education is surely new and uncommon in Poland, but we think, as SEDEC project, that can enrich both the panorama of science popularization outside and inside school system.
Jacek Piotr Szubiakowski
doaj  

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Science and scientists in the drawings of European children [PDF]

open access: yesJCOM: Journal of Science Communication, 2007
The first step of the SEDEC project has been a survey on teachers and pupils perception of science, scientists, and the European dimension of science. Different research actions have been organized for the different targets, and have been held in the six
Paola Rodari
doaj  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

School staff training: the opportunities offered by National Agencies in European countries [PDF]

open access: yesJCOM: Journal of Science Communication, 2007
In 2007 the Life Long Learning Programme (previously Socrates) of the European Commission has started. The programme offers to teachers, educators and policy-makers of the education sector the opportunity to be funded for participating at various ...
Chris Souvlis
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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