Results 241 to 250 of about 222,396 (315)

Partnership as a modulator of the effects of hormone replacement therapy in menopause. [PDF]

Front Glob Womens Health
Fiala L, Lenz J.
europepmc   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

Bridging Fear of Negative Evaluation and Cognitive Emotion Regulation Strategies: A Network Perspective on the Roles of Family Functioning and Self-Control. [PDF]

Depress Anxiety
Wang X, Li Y, Zhang D, Chang H.
europepmc   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source

Challenges and enablers of collaborative working in the voluntary, community, social, faith and enterprise sector: impact, effectiveness, and sustainability. [PDF]

Front Public Health
Vincent BP, Ali N, Egbutah C, Perkins K.
europepmc   +1 more source

Assessing tuberculosis stigma: a pooled multi-country descriptive analysis of 17 high-burden countries using a standardised tool. [PDF]

Front Public Health
Mok WMP, Malar J, Soltan V, Smyth C, Ul Eman K, Subakti A, Lobo R, Mukuhwa T, Tobaiwa D, Lunga M, Denysenko V, Kayowa B, Garcia D, Chamreun CS.   +13 more
europepmc   +1 more source

<b>E</b>quitable <b>P</b>alliative care <b>I</b>n the <b>C</b>ommunity through <b>P</b>rimary <b>C</b>are (EPIC-PC) study protocol: a realist study to propose a new integrated neighbourhood team approach to palliative care. [PDF]

BMJ Open
Mitchell S, Birtwistle J, Javeed A, Beng J, Hulbert L, Paley CA, Couchman E, Cocco P, Allsop M, Aunger J, Webb E, Dawkins B, Murtagh FEM, Evans C, Ziegler L.   +14 more
europepmc   +1 more source

Assessment of faculty members' perceptions towards community-oriented health professions education in Egypt: a concurrent convergent mixed-methods study. [PDF]

BMC Med Educ
Hamed O, Mekheimar SI, Abouzeid E, Mustafa SS, Amin MA, Abo-Halawa N, Hassan NH, AlSemeh AE, Talaat W.   +8 more
europepmc   +1 more source

Risk Perception and Communication, Plugged-In: Fifty Years of Process. [PDF]

Risk Anal
Warren GW, Duckett SM.
europepmc   +1 more source