Results 71 to 80 of about 36,329 (247)

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

open access: yesAdvanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li   +8 more
wiley   +1 more source

Body Image Perception of Chronic Kidney Disease Patients and Its Impact on Their Personal Relationships

open access: yesTurkish Journal of Nephrology, 2020
Objective: This study aimed to find the correlation between the interpersonal relationships of patients who had dialysis, kidney transplantation, and early-stage chronic renal failure (CRF) and the body image perception dependent on the therapy ...
Burcu Kıvrak Güçer   +1 more
doaj   +1 more source

Prevalence of stress among Iranian medical students: A questionnaire survey [PDF]

open access: yes, 2011
A cross-sectional study measured the frequency of self-reported stress symptoms among a weighted random sample of medical students in Isfahan, Islamic Republic of Iran. The data were gathered using the Kessler 10-item psychological distress scale.
Charkazi, A.   +5 more
core   +1 more source

Deep Brain Stimulation Induces Antidepressant Effects by Restoring High‐Fidelity Communication in the BNST‐NAc Circuit

open access: yesAdvanced Science, EarlyView.
This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv   +12 more
wiley   +1 more source

The Users of Institution Libraries [PDF]

open access: yes, 1978
published or submitted for ...
Duplica, Moya M.
core  

When feeling attractive matters too much to women: a process underpinning the relation between psychological need satisfaction and unhealthy weight control behaviors [PDF]

open access: yes, 2011
This study examined a process model linking psychological need satisfaction to unhealthy weight control behaviors. Female University students (N = 220; M age = 20.47; SD = 5.07) completed questionnaires measuring need satisfaction, appearance-contingent ...
Chatzisarantis, Nikos L.D.   +3 more
core   +1 more source

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo   +9 more
wiley   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong   +8 more
wiley   +1 more source

Predictors of Social Physique Anxiety among Recreational Bodybuilders

open access: yesPsychological Topics, 2020
This study aimed to determine the contribution of gender, age, intensity of exercise, perfectionism, perfectionistic self-presentation and eating attitudes in the explanation dimensions of social physique anxiety (SPA) in a sample of 345 male and female ...
Mirta Blažev   +3 more
doaj   +2 more sources

Body Image Perception: Adolescent Boys and Avatar Depiction in Video Games [PDF]

open access: yes, 2016
Research on mass media’s impact on body image has mostly been focused on females thus far. Of the little research that has been done on male body image, most of it has been focused on adult males, and therefore the effect of mass media on adolescent boys’
Raman, Usha
core   +1 more source

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