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Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong +13 more
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Social Innovation and Social Policy
2018This book provides an introduction to the concept of Social Innovation for readers interested in social and public policy. It explains why social and public policy analysts, policy makers and practitioners should become familiar with this idea, and explores how social innovation relates to key debates and core issues in public welfare.
Baglioni Simone, Sinclair Stephen
openaire +3 more sources
2014
This new edition of a social policy textbook provides a comprehensive introduction to social policy in the United Kingdom. It provides an overview of socio-economic, political and governmental contexts and historical developments in social policy. Other chapters deal with a variety of key social policy areas before the discussion moves on to European ...
Hugh Bochel, Guy Daly
openaire +5 more sources
This new edition of a social policy textbook provides a comprehensive introduction to social policy in the United Kingdom. It provides an overview of socio-economic, political and governmental contexts and historical developments in social policy. Other chapters deal with a variety of key social policy areas before the discussion moves on to European ...
Hugh Bochel, Guy Daly
openaire +5 more sources

