Results 101 to 110 of about 18,837,286 (349)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Development of a Positive Youth Development Program: Promoting the Mental Health of Stressful Adolescents Using Principles of Problem Solving Therapy

open access: yesThe Scientific World Journal, 2006
This paper outlines the proposal for the development, implementation, and evaluation of a positive youth development program that attempts to promote the mental health of stressful Chinese adolescents using principles of Problem Solving Therapy (PST ...
Daniel T.L. Shek, Joyce T.W. Chow
doaj   +1 more source

Managing Volunteer Retirement among Older Adults: Perspectives of Volunteer Administrators

open access: yesJournal of Public and Nonprofit Affairs, 2019
A large body of quantitative evidence demonstrates a link between volunteering and improved well-being, especially among older adults. Yet the research evidence pointing to the purported benefits of volunteering does not adequately address the unique ...
Allison R. Russell   +2 more
doaj   +1 more source

How do parking practices structure urban territorial communities? [PDF]

open access: yes, 2018
In this article we analyse the socio-spatial contexts and consequences of the practice of car parking in housing estates. Fredrik Barth’s idea of socially constructed boundaries and the theory of social practice form the theoretical basis of our analysis.
Bukowski, Andrzej   +2 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Determinants of frailty in primary care patients with COPD: the Greek UNLOCK study

open access: yesBMC Pulmonary Medicine, 2019
Background Frailty is a state of increased vulnerability that has a significant risk of unfavorable outcomes such as increased dependency and/or death, but little is known about frailty in people with chronic obstructive pulmonary disease (COPD).
Despo Ierodiakonou   +15 more
doaj   +1 more source

21st century social work: reducing re-offending - key practice skills [PDF]

open access: yes, 2005
This literature review was commissioned by the Scottish Executive’s Social Work Services Inspectorate in order to support the work of the 21st Century Social Work Review Group.
Batchelor, S.   +3 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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