Results 101 to 110 of about 3,389,027 (309)
A qualitative study of the challenges in rearranging community pharmacy service provision during the COVID-19 public health emergency: The prism of social practice theory. [PDF]
Public Health Pract (Oxf), 2021 Lubi K +4 more
europepmc +1 more source
Social practice theory (SPT) examines how shared routines and activities shape our daily lives and societies, focusing on actions within social contexts. Sitting at the intersection of key theoretical debates in the social sciences about what drives social action and behavior, it seeks a middle ground in the long-standing “structure-agency” debate ...
openaire +1 more source
A critical review of theory in social work journals: A replication study [PDF]
, 2007 : The purpose of this paper is multifold. Key aspects discussed include exploring the extent of theory discussion and progression in social work journals for the year 2004; discussing the necessity of theory in social work research and practice ...
Ballard, Kathy +8 more
core +1 more source
Social Work, Power and Performativity [PDF]
, 2012 In recent years, there have been a number of epistemological developments in social work. Further, there have been a number of theoretical approaches that have attempted to ground the concept of ‘power’ to understand organizational practice such as ...
Powell, Jason
core +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
A social practice theory of learning and becoming across contexts and time
Frontline Learning Research, 2016 This paper presents a social practice theory of learning and becoming across contexts and time. Our perspective is rooted in the Danish tradition of critical psychology (Dreier, 1997; Mørck & Huniche, 2006; Nissen, 2005), and we use social practice ...
William R. Penuel +3 more
doaj +1 more source
Understanding the nature and etiology of intimate partner violence and [PDF]
, 2011 Theoretical perspectives underlying hypotheses about the nature and etiology of intimate partner violence are important as they inform professionals how they should best respond to reduce or eliminate this social problem.
Dixon, Louise
core
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source