Results 141 to 150 of about 16,930,442 (358)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Philosophical dimensions of cultural policy
Філософія освітиAgainst the background of Russia’s full-scale war against Ukraine, the question of an effective cultural policy that would support national identity, contribute to the purification of consciousness from propaganda myths and preserve the heritage of ...
Алла Гужва
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Climate Pressures on Intangible Heritage
HeritageIntangible heritage comprises a wealth of knowledge, crafts, and skills that are passed down through the generations, embodied in our cultural practices.
Jenny Richards, Peter Brimblecombe
doaj +1 more source
Casting And Recasting Gender: Children Constituting Social Identities Through Literacy Practices [PDF]
, 2002 Considers how gender, identity and literacy are entangled and mutually constitutive. Concludes that social experience, desire, proximate others, and the ways in which children can draw upon these in the classroom are aspects of the situated condition ...
Anderson, Diane Downer
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Creating Excellence in Dementia Care: A Research Review for Ireland's National Dementia Strategy [PDF]
, 2012 Examines the prevalence and economic and social costs of dementia; policies, practices, and data on health and social care services in community-based, acute care, and long-term residential settings; and proposed elements for a new ...
Eamon O'Shea +2 more
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
(Im)possibilities of Autonomy: Social Movements In and Beyond Capital, the State and Development [PDF]
, 2008 Recently, we have witnessed the emergence of what appears to be a new set of claims in contemporary social movements based around the idea of autonomy. In this paper we interrogate this demand for autonomy.
Boehm, Steffen +2 more
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