Results 161 to 170 of about 16,930,442 (358)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
How European Protest Transforms Institutions of the Public Sphere - Discourse and Decision-Making in the European Social Forum Process [PDF]
Against the background of the alleged democratic deficit of EU institutions, this case study explores how politicization and emerging transnational public spaces in European protest movements innovate existing practices of discursive or grassroots ...
Nicole Doerr
core
Social Entrepreneurs and Innovation for the Unemployment [PDF]
, 2019 This research explored the social entrepreneurship factors to reduce the rate of unemployment in North Sumatra Indonesia. Social entrepreneurship is built through four main elements, namely social value, civil society, innovation, and economic activity ...
Sari, A. I. (Ade)
core
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
LandThe paper explores the correlation between the concepts of territoriality and social practices in the context of urban and rural (re-)production of space.
Anica Dragutinovic, Susanne Kost
doaj +1 more source
Economy of LIfe: Charismatic Dynamics and the Spirit of Gift [PDF]
, 2012 The dominant mode of globalization has mostly reinforced the disembedding of states and markets from the social practices and civic virtues of civil society writ large.
Pabst, Adrian
core
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Educational Leadership in Haiti: A Case Study of Innovative and Exemplary Leadership in a Fragile State [PDF]
, 2004 In this study, we consider three school leaders in Haiti who provide examples of innovative and exemplary leadership practices in the midst of challenging circumstances. Using a framework of innovative (Moolenaar, Daly, & Sleeger, 2010; Rogers, 2003) and
Arabaci, M +3 more
core +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source