Results 91 to 100 of about 2,742,920 (305)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Is everyone a mix of straight and gay? A social pressure theory of sexual orientation, with supporting data from a large global sample. [PDF]

Front Psychol, 2023
Epstein R, Wang H, Zankich VR.
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Présentation du texte d’Henri Janne « Introduction à la sociologie générale »

Sociologies, 2009
Introduction and presentation of Henri Janne’s text « Introduction à la sociologie générale », first published in Revue de l'Institut de Sociologie, 1951, n°3, pp. 345-392, and published here with the kind authorisation of the journal.
Claude Javeau
doaj  

The impact of sociocultural and psychological stress on the outcome of assisted reproductive technology in remarried families

Journal of Psychosomatic Obstetrics and Gynecology
Objective In China, there is a unique type of second marriage (SM) family where the woman is remarried, and the man is experiencing his first marriage. Additionally, the woman is older than the man.
Jiajia Zhai, Shibin Zhao, Guimin Hao
doaj   +1 more source

New nomads: the dispossession of the consumer in social housing [PDF]

, 2011
With the advent of flexible tenancies, marketised rents, the abolition of a consumer-focused regulator and the disbanding of the National Tenant Voice, three decades of efforts to induce consumer pressure in the English social housing sector have been ...
Bradley, Q
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

How (absent) fans influenced football during the COVID 19 pandemic?

Frontiers in Behavioral Economics
The fact that home football teams win more games than away teams has been largely discussed in the literature. Crowd factors appear to be the most dominant cause of this home advantage.
Luc Arrondel, Richard Duhautois, Baptiste Françon   +2 more
doaj   +1 more source

Perception of low social pressure and lack of capacity reduces vaccination compliance - The case of lumpy skin disease. [PDF]

Transbound Emerg Dis, 2022
Morgenstern M, Sok J, Klement E.
europepmc   +1 more source