Results 131 to 140 of about 2,728,948 (351)

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Thinness and Obesity: A Model of Food Consumption, Health Concerns, and Social Pressure [PDF]

open access: yes
The increasing concern of the policy maker about eating behavior has focused on thespread of obesity and on the evidence of a consistent number of individuals dietingdespite being underweight.
Davide Dragone, Luca Savorelli
core  

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Are Friendly Farmers Environmentally Friendly? Environmental Awareness as a Social Capital Outcome [PDF]

open access: yes
This paper examines the hypothesis that social capital at the individual level affects environmentally friendly practices. Social capital represents the social connectedness of the individual.
Jordan, Jeffrey L., Munasib, Abdul B.A.
core   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

The Triple Helix Perspective of Innovation Systems

open access: yes, 2010
Alongside the neo-institutional model of networked relations among universities, industries, and governments, the Triple Helix can be provided with a neo-evolutionary interpretation as three selection environments operating upon one another: markets ...
Leydesdorff, Loet, Zawdie, Girma
core   +2 more sources

Under Pressure? Longitudinal Relationships between Different Types of Social Media Use, Digital Pressure, and Life Satisfaction

open access: yesSocial Media + Society
Social media became the predominant medium for communicating, sharing updates, and monitoring other users. However, due to increasing use of social media, individuals might feel availability pressure to be online and production pressure to post content ...
Anja Stevic
doaj   +1 more source

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