Results 31 to 40 of about 499,783 (287)

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Social Network Pressure on Women and Men to Enter a Romantic Relationship and Fear of Being Single

open access: yesInterpersona: An International Journal on Personal Relationships, 2021
The romantic dyad is emphasized in society, which leads to the question of whether single (non-partnered) adults in emerging adulthood perceive pressure from their social network members to become partnered. The first purpose of this study was to examine
Susan Sprecher, Diane Felmlee
doaj   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Survey Responses on Desired Fertility in Patriarchal Societies: Community Norms vs. Individual Views

open access: yesComparative Population Studies, 2020
The paper deals with a problem regularly faced by survey studies of patriarchal communities, i.e. communities with a high authority of senior generations and a low level of women’s autonomy.
Konstantin Kazenin, Vladimir Kozlov
doaj  

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Institutional Co-Creation Interfaces for Innovation Diffusion during Disaster Management

open access: yesManagement Dynamics in the Knowledge Economy, 2017
This paper discusses the concept of Resilient and Green Supply Chain Management (RGSCM) implementation in South Eastern Europe (SEE) from the point of view of understanding the structure of the inter-organizational (institutional) interfaces involved in ...
Adrian SOLOMON   +2 more
doaj  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Antihypertensive drug effects according to the pretreatment self-measured home blood pressure: the HOMED-BP study

open access: yesBMJ Open, 2020
Objectives To clarify whether or not the antihypertensive drug effect is proportional to the baseline pretreatment self-measured home blood pressure (HBP) in accordance with the law of initial value (Wilder’s law).Design A post-hoc analysis of a ...
Masahiro Kikuya   +6 more
doaj   +1 more source

Research on the Influence of Media Internalized Pressure on College Students’ Sports Participation—Chained Intermediary Analysis of Social Physique Anxiety and Weight Control Self-Efficacy

open access: yesFrontiers in Psychology, 2021
Purpose: Discuss the relationship among college students’ media internalized pressure, social physique anxiety, weight control self-efficacy, and sports participation in providing a reference for promoting college students to develop healthy and ...
Yiyi Ouyang   +5 more
doaj   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

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