Results 81 to 90 of about 2,728,948 (351)

Culinary resilience in a globalized world: how social norms negotiate tradition and adaptation

Business, Management and Economics Engineering
Purpose – This study investigates how macro-level forces and micro-level cultural constructs shape food culture resilience in different societies. It bridges the knowledge gaps between cultural preservation and adaptation.
Mangirdas Morkūnas, Yufei Wang, Lucia Vilčekova   +2 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

See you on Facebook: the effect of social networking on human interaction [PDF]

This paper proposes an evolutionary framework to explore the dynamics of social interaction in an environment characterized by online networking and increasing pressure on time.
Antoci, Angelo, Sabatini, Fabio, Sodini, Mauro   +2 more
core   +1 more source

Effect of Social Pressure and Trust on Organizational Legitimacy: A Retailing Sector Perspective

Journal of Economy Culture and Society
Enterprises operate in complex and competitive environments where stakeholders have become more demanding regarding corporate behavior. Organizations must respond to social demands and build trust among stakeholders to be perceived as legitimate ...
Susana Diaz Iglesias, Gabriel Cachón Rodríguez, Giorgia Miotto   +2 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Divergent effects of listening demands and evaluative threat on listening effort in online and laboratory settings

Frontiers in Psychology
ObjectiveListening effort (LE) varies as a function of listening demands, motivation and resource availability, among other things. Motivation is posited to have a greater influence on listening effort under high, compared to low, listening demands ...
Peter J. Carolan, Peter J. Carolan, Antje Heinrich, Antje Heinrich, Kevin J. Munro, Kevin J. Munro, Rebecca E. Millman, Rebecca E. Millman   +7 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

The relationship between physical appearance perfectionism on subthreshold depression in college students: the role of gender and fear of negative evaluation

Frontiers in Public Health
IntroductionOver the past decades, subthreshold depression has emerged as a significant mental health concern among college students, with prevalence rates reaching 40.8%.
Yiru Wei, Hong Chen, Bo Sun, Lingli Kong
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

The key role of institution pressure on green supply chain practice and the firm's performance [PDF]

, 2019
Purpose: This study was conducted to investigate the influence of isomorphism institutional theory on green supply chain management (GSCM) and firm performance by using the structural equation model (SEM) to explain the driving factors of reducing the ...
Saenchaiyathon, Krittapha, Wongthongchai, Jirawat   +1 more
core   +2 more sources