Results 171 to 180 of about 14,106,338 (309)

HSE National Office for Suicide Prevention annual report 2010

open access: yes, 2011
Annual report published by the HSE National Office for Suicide Prevention (NOSP), summarising its programme of work, expenditure, and details of funded services and initiatives from over 20 NGOs working in mental health and suicide ...
HSE National Office for Suicide Prevention (NOSP)
core  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Risk factors for adolescent cannabis use following partial cannabis legalization in Germany: a cross-sectional study in secondary schools. [PDF]

open access: yesSubst Abuse Treat Prev Policy
Trümpelmann M   +10 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Not Just a Strategy, But the Heartbeat of Our Work: The Importance of Youth Engagement in Drug-Free Communities Coalitions. [PDF]

open access: yesJ Public Health Manag Pract
Taylor C   +5 more
europepmc   +1 more source

CDC Suicide Prevention Strategic Plan

open access: yes
Suicide is a critical public health problem in the United States. Despite a national strategy for suicide prevention and multiple federal, national, and state/local initiatives, as well as a large community of suicide prevention champions, suicide rates ...

core  

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

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