Results 81 to 90 of about 14,106,338 (309)

Social protection as a strategy for HIV prevention, education promotion and child marriage reduction among adolescents: a cross-sectional population-based study in Lesotho

BMC Public Health
Background Lesotho’s government has shown consistent efforts to implement social protection programmes. However, while recent evidence established a positive causal relationship between some of these programmes and food security there is little evidence ...
Lucas Hertzog, Lucie Cluver, Boladé Hamed Banougnin, Maria Granvik Saminathen, Madison T. Little, Martina Mchenga, Rachel Yates, William Rudgard, Laura Chiang, Francis B. Annor, Viani Picchetti, Greta Massetti, Marisa Foraci, Rantsala Sanaha, Elona Toska   +14 more
doaj   +1 more source

Social marketing made simple [PDF]

"Social Marketing Made Simple is a lighter version of the CDCynergy: Social Marketing edition product. This tool is based on best practice social marketing principles, and assists in developing, implementing and evaluating an effective social marketing ...

core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Expectations of Failure: Political Risks in the Moral Economy of Ignorance and Social Injustice

Sociologica
We are observing how contemporary failure regimes increasingly challenge ignorance and social injustice, and how this opens expectations for public policy to move beyond effectiveness and to pursue more emancipatory and progressive aims.
Adriana Mica, Mikołaj Pawlak, Paweł Kubicki   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Task-shifting point-of-care CD4+ testing to lay health workers in HIV care and treatment services in Namibia

African Journal of Laboratory Medicine, 2017
Introduction: Access to CD4+ testing remains a common barrier to early initiation of antiretroviral therapy among persons living with HIV/AIDS in low- and middle-income countries.
Francina Kaindjee-Tjituka, Souleymane Sawadogo, Graham Mutandi, Andrew D. Maher, Natanael Salomo, Claudia Mbapaha, Marytha Neo, Anita Beukes, Justice Gweshe, Alexinah Muadinohamba, David W. Lowrance   +10 more
doaj   +1 more source

Evaluation of the uptake of tuberculosis preventative therapy for people living with HIV in Namibia: a multiple methods analysis

BMC Public Health, 2020
Background In 2016, Namibia had ~ 230,000 people living with HIV (PLHIV) and 9154 new tuberculosis (TB) cases, including 3410 (38%) co-infected cases. TB preventative therapy (TPT), consisting of intensive case finding and isoniazid preventative therapy,
Clay Roscoe, Chris Lockhart, Michael de Klerk, Andrew Baughman, Simon Agolory, Michael Gawanab, Heather Menzies, Anna Jonas, Natanael Salomo, Negussie Taffa, David Lowrance, Katherine Robsky, Deanna Tollefson, Eric Pevzner, Ndapewa Hamunime, Farai Mavhunga, Helena Mungunda   +16 more
doaj   +1 more source

New directions in sexual assault prevention

, 2003
The central question that faces all of us who are committed to non-violence is how can we prevent sexual assault. This is a question that has been a concern of feminist politics for over a century and more recently for the last three decades.
Carmody, Moira
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source