Results 41 to 50 of about 5,935,135 (295)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
System Transformation: Achievements and Social Problems in Poland [PDF]
, 2015 The present book “Poland – History, Culture and Society. Selected Readings” is the third edition of a collection of academic texts written with the intention to accompany the module by providing incoming students with teaching materials that will assist ...
Warzywoda-Kruszyńska, Wielisława
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The Problem of Social Protection in Albania [PDF]
, 2013 The aim of this paper is to analyze the social protection system in Albania during the last two decades. It highlights some of the problems and issues which are closely associated with elements of social security, as a phenomenon that focuses on finding ...
Dragoshi, Gert, Shkreli Axhemi, Arlinda
core +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Prace Komisji Geografii Przemysłu Polskiego Towarzystwa Geograficznego, 2019 The report provides an assessment of the innovation factor in the reindustrialisation of Eastern Siberia, based on data on R&D costs and the introduction of innovative products. The Krasnoyarsk Territory has the greatest innovative potential, followed by
Vera Rudneva
doaj +1 more source
Social interaction as a heuristic for combinatorial optimization problems
, 2010 We investigate the performance of a variant of Axelrod's model for dissemination of culture - the Adaptive Culture Heuristic (ACH) - on solving an NP-Complete optimization problem, namely, the classification of binary input patterns of size $F$ by a ...
Fontanari, Jose F.
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Integrated education, intergroup relations, and political identities in Northern Ireland [PDF]
, 2007 Published as Hayes, BC., McAllister, I. & Dowds, L. (2007). 'Integrated education, intergroup relations, and political identities in Northern Ireland.' Social Problems 54(4) pp. 454-482.© 2007 by Society for the Study of Social Problems, Inc. Copying and
Dowds, Lizanne +2 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Intercompany training as production pedagogical process
Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2016 The article explains the corporate training as a coordinated interaction of educational and industrial processes in the preparation of in-demand professionals.
Evgeny A. Korchagin +2 more
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