Results 71 to 80 of about 335,014 (259)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Patient Preferences for Low Back Pain Treatments in Iran: A Discrete Choice Experiment

Patient Preference and Adherence
Moslem Soofi,1 Behzad Karamimatin,2 Zahra Alipoor,1,3 Ali Kazemi-Karyani1 1Social Development and Health Promotion Research Center, Health Policy and Promotion Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran; 2Research Center for ...
Soofi M, Karamimatin B, Alipoor Z, Kazemi-Karyani A   +3 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Efficacy of the Theory-Based Program for Improvement of Sleep Hygiene Behaviors of the Elderly [PDF]

پزشکی بالینی ابن سینا
Background and Objective: Disorders related to the quality and quantity of sleep are among the most important issues of old age. In this regard, the present study aimed to determine the efficacy of an educational program based on the theory of planned ...
Mehdi Mirzaei-Alavijeh, Habibolah Khazaie, Mahshad Taherpour, Farzad Jalilian   +3 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The effect of the work-family conflict, subjective socio-economic status, and physical activity on the perceived quality of life of working women in Iran: the mediating role of quality of work life

BMC Women's Health
Introduction The conflict between work and family responsibilities has created many challenges for working women in Iran. This study aimed to examine the effect of work-family conflict (WFC), subjective socio-economic status (SSS), and physical activity (
Nader Rajabi-Gilan, Shirin Zardoshtian, Neda Sarabi, Mehdi Khezeli   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Engagement of coMmunity through Participatory learning and action for cOntrol and preVEntion of type II Diabetes and its Risk factors (EMPOWER-D) - A Protocol for a Cluster Randomised Controlled Trial

BMC Public Health
Background In Pakistan, every third adult is suffering from diabetes. Community-based approaches have the potential to be effective in preventing diabetes.
Khalid Rehman, Amber Tahir, Sara Imtiaz, Zohaib Khan, Saima Afaq, Asima Khan, Inayat Shah, Mona Kanaan, Noor Sanauddin, Nadia Khaleeq, Mariam Abdeali, Simon Walker, Farrukh Ahmed, Hannah Maria Jennings, Sajid Ali, Sheraz Fazid, Abdul Rahman Shahab, Maria Ishaq Khattak, Rubia Zafar, Abdul Basit, Kamran Siddiqi, Zia Ul Haq   +21 more
doaj   +1 more source