Results 31 to 40 of about 348,398 (258)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Understanding territorial inequalities in decentralised welfare systems: early childhood education and care system expansion in Croatia

Public Sector Economics, 2023
The decentralised provision of social services raises concerns about availability of services in different geographical areas, particularly in low- and middleincome countries with weak governance and fiscal redistributive capacities.
Ivana Dobrotic, Teo Matkovic
doaj   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Self-reported depression and social support are associated with egocentric network characteristics of HIV-infected women of color

BMC Women's Health, 2020
Background We explore the social network characteristics associated with depressive symptoms and social support among HIV-infected women of color (WOC). Methods Network data were collected from 87 HIV-infected WOC at an academic Infectious Disease clinic
Lynne C. Messer, E. Byrd Quinlivan, Adaora Adimora, Katya Roytburd   +3 more
doaj   +1 more source

The potential of data linkage for improving social care provision

International Journal of Population Data Science, 2023
Objectives The main objective of the project was to link case-level data from Children’s Social Care (CSC) service with household-level data on means-tested benefits, in order to analyse the dynamic relationship between families’ financial situation and
Magdalena Rossetti, Rick Hood
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

ENSURING WELFARE PROVISION THROUGH INTERSECTORAL SOCIAL RESPONSIBILITY

Three Seas Economic Journal
The study addresses the transformation of welfare provision systems under conditions of heightened socio-economic uncertainty, structural risks, budget restrictions, and multidimensional crisis shocks. It proceeds from the premise that traditional state-
Olena Sova, Vladyslav Kuznietsov
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

‘Being able to work has kept our life fairly constant:’ reconciling social practice models to assess the impact of (infra)structural inequities on household wellbeing during the COVID-19 pandemic

Environmental Research: Infrastructure and Sustainability, 2023
Social practice theory offers a multidisciplinary perspective on the relationship between infrastructure and wellbeing. One prominent model in practice theory frames systems of provision as the rules, resources, and structures that enable the ...
Sonya Ahamed, Chelsea Schelly, Kristin Floress, William Lytle, Holly Caggiano, Cara L. Cuite, Charles Wallace, Ryan Cook, Rebekah Jarvis, Rachael Shwom, David Watkins   +10 more
doaj   +1 more source