Results 231 to 240 of about 6,448,088 (302)

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Social Drivers of Health in Pediatric Perioperative Care. [PDF]

Anesthesiology
Willer BL.
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Conceptualisation and operationalisation of social support in health interventions: a scoping review. [PDF]

BMJ Public Health
Kersey J, Lee S, Connor LT, Shyres S, Alimi E, Rojas Serrano N, Kim MY, Van Sang P, Casem N, Le C, Lipsey K, Donoso Brown E.   +11 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Quality of Life, Menopausal Symptoms, Insomnia and Depression in Peri- and Post-Menopausal Women: A Cross-Sectional Study. [PDF]

Med Sci Monit
Raczkiewicz D, Sarecka-Hujar B, Gujska JH, Wdowiak A, Wróbel A, Patyra W, Bojar I.   +6 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Navigating paradox in child welfare: implications for improvement science in complex human service systems. [PDF]

Front Health Serv
Evaldsson C, Kjellström S.
europepmc   +1 more source

Quality-of-life assessment in autistic adults with lower support needs: gaps and emerging challenges. [PDF]

Front Psychiatry
Fernández M, Wojcik DZ, Díez E.
europepmc   +1 more source