Results 91 to 100 of about 7,824,707 (340)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Developing agency in a writing centre context : a Social Realist interpretation
The aim of this article is to explore how aspects of a Social Realist theoretical framework could be understood in relation to my professional development as a writing centre consultant and manager.
Slemming, Fatima
doaj +1 more source
Looking for the (missing) indicators of social sustainability - Evidence from sustainability standards in the coffe sector [PDF]
Rising consumer interest for ethical and/or responsible products and the growing interweaving of social and environmental issues question the ability of scientific methods to correctly assess social impacts. To this day however, no consensus has yet been
Lemeilleur, Sylvaine, Vagneron, Isabelle
core
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
An Analysis of Semantic Waves: Maton’s Legitimation Code Theory for Cumulative Knowledge-Building
This paper aims to state that knowledge blindness in educational research has severe obstacles to understanding knowledge development. Karl Maton offers sociological concepts of Legitimation Code Theory (LCT) - 'semantic gravity' and 'semantic density' –
Yolanda Ramadhan
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Mozart plays the intermediary between three picture books by Maurice Sendak: Outside Over There, Dear Mili, and We Are All in the Dumps with Jack and Guy, in which Mozart is explicitly depicted. This article focuses on the last two works of this trilogy,
Gaëlle Levesque
doaj +1 more source
Pre-Darwinian species change: reincarnation and transformism in George Sand’s Évenor et Leucippe [PDF]
No abstract ...
Mathias, Manon
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

