Results 101 to 110 of about 7,824,707 (340)

Towards New Definitions of Eastern and Central European Cinematic Social Realism

Kwartalnik Filmowy
The article addresses the issue of defining social realism within the context of Eastern and Central European cinema. Although this region’s cinema has long been associated with films that combine social issues with the conventions of realism, a ...
Karolina Kosińska
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

‘‘The provocation is titillating.’’ Sven Wernström in Iceland

Barnboken: Tidskrift för Barnlitteraturforskning, 2012
The article discusses the reception and impact of Sven Wernström’s views and works in Iceland. In particular, it retraces the controversy which surrounded the 1978 translation of his book Kamrat Jesus (1971) and recounts the heated debate over the book ...
Olga Holownia
doaj   +1 more source

Liberate your avatar; the revolution will be social networked [PDF]

, 2009
This paper brings together the practice-based creative research of artists Charlotte Gould and Paul Sermon, culminating in a collaborative interactive installation that investigates new forms of social and political narrative in multi-user virtual ...
Gould, CE, Sermon, P
core   +1 more source

'A habitual disposition to the good': on reason, virtue and realism [PDF]

, 2015
Amidst the crisis of instrumental reason, a number of contemporary political philosophers including Jürgen Habermas have sought to rescue the project of a reasonable humanism from the twin threats of religious fundamentalism and secular naturalism.
Agamben G., Agamben G., Aristotle, Bauman Z., Bellah R., Benedict, Berlin I., Bruni L., Debord G., Edelman M., Foucault M., Geuss R., Goetz S., Gray J., Gray J., Gray J., Habermas J., Habermas J., Habermas J., Habermas J., Habermas J., Habermas J., Habermas J., Hirst P. Q., Jaspers K., Juergensmeyer M., Juergensmeyer M., Macintyre A., Manent P., Michéa J.-C., Milbank J., Moreland J. P., Muralt A. D., Nancy J.-L., Nicholls D., Northcott M., Pabst A., Planinc Z., Plato, Polanyi K., Popper K. R., Rawls J., Rawls J., Rawls J., Rawls J., Rawls J., Sandel M. J., Sandel M. J., Scott J. C., Taylor C., Taylor C., Taylor C., Taylor C., Thompson E. P., Williams B., Williams B., Wolin S. S.   +56 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Documentary Photography and the Representation of Life on the Streets in Two Works by Martha Rosler and Jeff Wall: Ethical and Aesthetic Considerations

IdeAs, 2019
Four decades separate Martha Rosler’s The Bowery in two inadequate descriptive systems (1974-1975) from Jeff Wall’s Approach (2014), two representations of life on the streets.
Gwen Cressman
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source