Results 31 to 40 of about 9,712,110 (347)

Stories of how to give or take – towards a typology of social policy reform narratives

open access: yesPolicy & Society, 2019
Narrative stories are crucial to policy change, as they decisively contribute to how policy problems and policies are defined. While this seems to apply for social policy in particular, narrative stories have remained under-researched and not ...
S. Blum, Johanna Kuhlmann
semanticscholar   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

Healthcare use of young Finnish adults with mental disorders – profiles and profile membership determinants

open access: yesBMC Primary Care
Background Comprehensive, timely, and integrated primary care services have been proposed as a response to the increased demand for mental health and substance use services especially among young people.
Visa Väisänen   +4 more
doaj   +1 more source

Do Employees’ Sickness Absences React to a Change in Costs for Firms? Evidence from a Natural Experiment [PDF]

open access: yes, 2020
We analyse the impact of a social security reform that changed the costs incurred by firms due to sickness absences. The reform abolished a compulsory insurance for firms, which insured them against the wages paid to sick blue‐collar workers.
Böheim, René, Leoni, Thomas
core   +1 more source

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

open access: yesAdvanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham   +9 more
wiley   +1 more source

Medical deserts in Finland: measuring the accessibility and availability of primary health care services

open access: yesBMC Health Services Research
Background Well-functioning primary health care (PHC) systems are needed to meet the challenges of aging populations and increasing care needs. However, “medical deserts”, areas with poor accessibility and availability of PHC services, remain a ...
Visa Väisänen   +4 more
doaj   +1 more source

Neighbourhood Satisfaction Among Municipal Tenants in the Helsinki Metropolitan Area

open access: yesTidsskrift for boligforskning
This article analyses municipal tenants’ neighbourhood satisfaction (NS) in the Helsinki metropolitan area. If social mixing has managed to equalise differences related to the residential environment across different social groups, perceived ...
Katriina Rosengren, Timo M. Kauppinen
doaj   +1 more source

Révolution sociale et utopie chez les premiers Fabiens (1884-1890) : un positionnement complexe

open access: yesCahiers Victoriens et Edouardiens, 2019
Forty years after the demise of Owenism and about ten years after the dissolution of the First International (the IWMA) in the wake of the Paris Commune, there was a Socialist Revival in Britain.
Marie Terrier
doaj   +1 more source

The Boston Women’s Educational and Industrial Union: When Business Undergirded Claims to Political Participation (1877-1920)

open access: yesTransatlantica, 2020
This article is a case study of a Progressive Era women’s voluntary association, the Women’s Educational and Industrial Union of Boston. It is an examination of the ways in which some reform organizations headed and staffed by women could embrace and ...
Jeanne Boiteux
doaj   +1 more source

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