Results 251 to 260 of about 14,723,140 (335)

Animals as Communication Partners: Ethics and Challenges in Interspecies Language Research. [PDF]

Animals (Basel)
Mamzer H, Kuchtar M, Grzegorzewski W.
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Understanding barriers and facilitators of adherence to lifestyle changes in prediabetes: a qualitative study. [PDF]

Int J Qual Stud Health Well-being
Carvalho-Azevedo AS, Sebastián-Hernández R, Abbate M, Fresneda S, Arias-Fernández M, Yañez AM, Bennasar-Veny M, Moreno-Mulet C.   +7 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Loneliness in older adults: an assessment on social network usage, social support, and active aging. [PDF]

BMC Geriatr
Yıldız MK, Çal A.
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

The Role of Gaze in Shaping Forms of Reflective Practice: A Legitimation Code Theory Analysis of Clinical Supervision in Danish Primary Care. [PDF]

Scand J Caring Sci
Hindhede AL, Hald HH, Andersen C.
europepmc   +1 more source

Enacted Restoration of Selfhood: A Kierkegaardian Perspective on Self-harm Among People with Mental Illness. [PDF]

Cult Med Psychiatry
Jønsson ABR, Li EX, Steno AM.
europepmc   +1 more source

Incident Depression in Relation to Contextual Isolation among Established Long-stay Residents of US Nursing Homes. [PDF]

J Nurs Home Res Sci
Jesdale BM, Yuan Y, Nielsen NN, Lapane KL.   +3 more
europepmc   +1 more source