Results 221 to 230 of about 13,565,768 (288)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

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openaire   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Machine learning methods and schizophrenia spectrum disorders: a scoping review. [PDF]

BMJ Open
Rivera LA, Costa-Dookhan KA, Raj V, Dissanayake J, Siddiqui I, Hahn M, Rotenberg M, Maslej M, Foussias G.   +8 more
europepmc   +1 more source

Patient-reported outcome measures within European cohorts of severely injured patients: a systematic review and meta-analysis. [PDF]

Eur J Trauma Emerg Surg
van den Berg L, van Ditshuizen JC, Leliefeld PHC, den Hartog D, Giannakópoulos GF, Verhofstad MHJ, de Jongh MAC.   +6 more
europepmc   +1 more source

Age-Moderated Associations Between Social Support and Loneliness in Latino Adults with Cardiovascular Disease. [PDF]

Hisp Health Care Int
Falk DS, Melgoza E, Cabrera A, Vazquez CE.   +3 more
europepmc   +1 more source

Community-Based Prevention: Findings From Nearly 3 Decades of the Drug-Free Communities Support Program. [PDF]

J Public Health Manag Pract
O'Donnel BK, Moss BG, Cooley KA, Morales V.   +3 more
europepmc   +1 more source

Empowering youth with disabilities through community-based approaches: a scoping review protocol on livelihood and social inclusion. [PDF]

BMJ Open
Maholo C, Mayat N, Lorenzo T, Naidoo N.
europepmc   +1 more source