Results 251 to 260 of about 21,515,074 (353)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Independent companies in the tobacco supply chain: transparency and environmental social governance. [PDF]

Tob Control
Dunwoodie Stirton F, Hiscock R, Mehegan J, Gallagher AWA, Bloomfield MJ.   +4 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Sunburn Prevalence Among US High School Students, Youth Risk Behavior Survey, United States, 2023. [PDF]

Prev Chronic Dis
Holman DM, Saelee R, Kiplagat SJ, Julian AK.   +3 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Social Inequalities report

Report on social Inequalities in healthy ageing.
openaire   +1 more source

Low social capital at work is associated with increased risk of perceived age discrimination: results from a prospective cohort study. [PDF]

Eur J Ageing
Meng A, Albertsen K, Clausen T, Sundstrup E, Andersen LL.   +4 more
europepmc   +1 more source

A narrative qualitative study of maternal and perinatal death surveillance and patient referral practices among Traditional Birth Attendants in East Central Uganda. [PDF]

Discov Public Health
Kagoya EK, Auma P, Babuya J, Gamubaka R, Asabawebwa D, Kawala E, Waako P, Mugabi S, Ssemwanga B, Kayemba F, Aturinda C, Mutunda BD, Mugabe K, Mugahi R.   +13 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

V-CHIMERA: An Immune-Inspired Verified Framework for Organizational Cyber Crisis Response Under Misinformation. [PDF]

Biomimetics (Basel)
Alghamdi F, Alqithami S.
europepmc   +1 more source