Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Social semiotics and social representations [PDF]
A social representations approach offers an empirical utility for addressing myriad social concerns such as social order, ecological sustainability, national identity, racism, religious communities, the public understanding of science, health and social marketing.
openaire +2 more sources
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
THE SOCIAL REPRESENTATION OF PHYSICAL PUNISHMENT AMONG PARENTS OF PRIMARY CLASSES CHILDREN
The research was focused on studying the content of social representations (SR) among parents of childrenfrom primary classes’, highlighting by gender the constitutive elements of this representations.
Otilia STAMATIN
doaj
Violența simbolică: discurs și reprezentări sociale în campania pentru alegerile prezidențiale din 2014 (Symbolic violence: discourse and social representations during the 2014 prezidential campaign) [PDF]
Societies work on relations of power and domination, the political practices and even groups involved in politics are generating violence. Romanian public space was gradually taken over by symbolic violence, an act of power between the political elites ...
Mirabela AMARANDEI
doaj
Use of Hypothetical Situations as a Methodological Resource in a Social Representations Study [PDF]
: Gender-based violence is a multifaceted problem, recurrently addressed in different fields, and its approach is always challenging. The study aimed to characterize the use of hypothetical situation vignette as a methodological resource in the study of ...
Mariana Schubert Lemos +1 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
In this article, social representations of Europe are studied in case of Turkish university students. The sample consists of 382 students from various departments of Faculty of Letters at Ege University.
Ilkay SUDAS, Melek GOREGENLI
doaj
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source

