Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Correction: Social representations of COVID-19 by the nursing team of an intensive care unit. [PDF]
da Silva RC +8 more
europepmc +1 more source
Rehearsing post-Covid-19 citizenship: Social representations of UK Covid-19 mutual aid. [PDF]
O'Dwyer E +2 more
europepmc +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Social representations and foreign language learning
Social representations (SR) are one the most influencing social-psychological factors involved in foreign language (FL) learning (Maurer, 2013). In particular, it has been proved that speakers’ representations of languages and their cultures influence ...
Charifa Eddahani +2 more
doaj
Vaccination: a look at the social representations of Brazilian children. [PDF]
de Gaspi S +4 more
europepmc +1 more source
Social representations of pregnant women about high-risk pregnancy: repercussions for prenatal care. [PDF]
Pereira AA +6 more
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Between science and transcendence: social representations of professionals about religiosity and spirituality in pediatric terminality. [PDF]
Azevedo TGL, Ferreira MA.
europepmc +1 more source

