Results 211 to 220 of about 9,372,448 (341)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Social representations of COVID-19 by the nursing team of an intensive care unit. [PDF]

BMC Nurs
da Silva RC, Gonçalves Ribeiro Araujo B, Rentz LBPA, da Silva Rangel Ribeiro G, de Almeida RMF, de Souza TV, Ferreira MA, Tura LFR, Apostolidis T.   +8 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Exploring the social representations of breastfeeding among mothers and grandmothers in Uruguay using word association. [PDF]

Int Breastfeed J
Girona A, de Pena L, Sant'Anna HC, Ares G, Heck R.   +4 more
europepmc   +1 more source

A Preliminary Study on the Validity and Stability of Projective Methods: An Application of the Structural Approach of Social Representations with Traditional Mexican Cheeses. [PDF]

Foods, 2022
Rojas-Rivas E, Thomé-Ortiz H, Espinoza-Ortega A.   +2 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Correction: Social representations of COVID-19 by the nursing team of an intensive care unit. [PDF]

BMC Nurs
da Silva RC, Araujo BGR, Rentz LBPA, Ribeiro GDSR, de Almeida RMF, de Souza TV, de Assunção Ferreira M, Tura LFR, Apostolidis T.   +8 more
europepmc   +1 more source

Rehearsing post-Covid-19 citizenship: Social representations of UK Covid-19 mutual aid. [PDF]

Br J Soc Psychol, 2022
O'Dwyer E, Souza LGS, Beascoechea-Seguí N.   +2 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Intentions, practices, and social representations regarding breastfeeding among women experiencing social disadvantage: findings from the qualitative component of the ECAIL trial. [PDF]

Int Breastfeed J
Poquet D, de Lauzon-Guillain B, Ley D, Charles MA, Sauvegrain P, Lioret S.   +5 more
europepmc   +1 more source