Chronotype, cognitive outcomes, and neural dynamics: recent evidence and potential mechanisms with implications for perioperative period. [PDF]
Liu Y +6 more
europepmc +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
The Current Landscape of School Health Research in the Philippines: A Scoping Review. [PDF]
Villanueva EQ.
europepmc +1 more source
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Validation of cough evaluation test in subacute cough. [PDF]
Li J +7 more
europepmc +1 more source
Hajnalka Fenyes (ed.) (2015). Volunteering and New Type of Volunteering Among the Higher Education Students. [onkentesseg Es Uj Tipusu Onkentesseg a Felsooktatasi Hallgatok Koreben.] Debrecen: Debrecen University Press. [PDF]
Kovacs, Karolina Eszter, Valeria, Markos
core +1 more source
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Impacts of early childhood caries on the mental development. [PDF]
Dereli̇oğlu SŞ +9 more
europepmc +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source

