Results 61 to 70 of about 5,410,250 (357)
We combine data from global forest resource assessments with a forest model to quantify the role of major drivers of net carbon fluxes from global forest biomass at national resolution between 1990 and 2020.
Julia Le Noë +5 more
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
As the fear of the spread of COVID-19 has faded, governments around the world are moving to lift strict behavioral restrictions. How should human resource management at overseas subsidiaries adapt to these system changes?
Keisuke Kokubun +2 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Transhumanism, managerism and the special military operation in Ukraine
The article analyzes two ideologies that are the most important for the modern Transhumanism and managerialism as two ideologies most significant for the modern Western world have been analyzed. The study of these issues was carried out in the context of
V. V. Kovalev
doaj +1 more source
Built structures influence patterns of energy demand and CO2 emissions across countries
Built structures, i.e. the patterns of settlements and transport infrastructures, are known to influence per-capita energy demand and CO2 emissions at the urban level.
Helmut Haberl +8 more
doaj +1 more source
Content Analysis of Grade Three Social Studies Learning Resources on Provincial Symbols [PDF]
Julius V Sarabia
openalex +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source

