Results 51 to 60 of about 211,263 (254)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Occupational safety and health aspects of corporate social responsibility reporting in Japan: comparison between 2012 and 2020. [PDF]
BMC Res Notes, 2022 Shimizu T +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Corporate Social Responsibility and Web Reporting
Inquiry, 2016 Corporate Social Responsibility (CSR) represents the obligation of an individual, or in this case the company, to be beneficial to the society. The concept will no longer consider profit maximization of a company but to take care of the society and the environment in which they operate.
Emil Knezović +2 more
openaire +2 more sources
Impact of economic, environmental, and corporate social responsibility reporting on financial performance of UAE banks. [PDF]
Environ Dev Sustain, 2023 Ellili NOD, Nobanee H.
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
ANALYSIS OF CORPORATE SOCIAL REPORTING RESPONSIBILITY OF STATE AND REGIONAL OWNED ENTERPRISES [PDF]
Eurasia: Economics & Business, 2019 Disclosure of corporate social responsibility is an illustration of the implementation of corporate social responsibility. This study aimed to analyze the information needed in the field of social responsibility in line with the business of SOE/ROE in ...
Muliati, Iqbal M., Arung G.M.
doaj
The Mechanisms of Chief Executive Officer Characteristics and Corporate Social Responsibility Reporting: Evidence From Chinese-Listed Firms. [PDF]
Front Psychol, 2022 Zhao X, Wang M, Zhan X, Liu Y.
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source