Results 21 to 30 of about 1,400 (241)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

A TRADITIONAL FALSE PROBLEM: THE RIGORISM OF KANTIAN MORAL AND POLITICAL PHILOSOPHY. THE CASE OF VERACITY [PDF]

open access: yes, 2012
According to many of its traditional critics, the main weakness in Kantian moral-political philosophy resides in its impossibility of admitting exceptions.
MIHAI NOVAC
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

John Rawls and the New Kantian Moral Theory [PDF]

open access: yes, 2005
I argue that Rawls’ reading of Kant has been a major influence on the work of some contemporary Kantian scholars. Rawls’ influence on the new Kantian moral theory can be recognized in several points: a) the conception of philosophy as a “deeply practical
González, A.M. (Ana Marta)
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Atarashiki mura versus Xincun. On the Chinese reception of a Japanese model of alternative lifestyle as a case study on standard and deviation [PDF]

open access: yes, 2013
Englische Übersetzung von: Müller-Saini, Gotelind: Atarashiki mura versus Xincun : zur chinesischen Rezeption eines japanischen Modells alternativer Lebensführung. In: Norm und Abweichung (2001), S.
Müller-Saini, Gotelind
core   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah   +7 more
wiley   +1 more source

Kant, the Duty to Promote International Peace, and Political Intervention [PDF]

open access: yes, 1995
Kant argues that it is the duty of humanity to strive for an enduring peace between the nations. For Kant, political progress within each nation is essential to realizing lasting peace, and so one would expect him to view political intervention- defined ...
van der Linden, Harry
core   +1 more source

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