Results 21 to 30 of about 11,654,900 (214)

Finding overlapping communities in social networks

open access: yesProceedings of the 13th ACM Conference on Electronic Commerce, 2012
19 ...
Sanjeev Arora   +3 more
openaire   +2 more sources

Computational approaches in rigorous sociology: agent-based computational modeling and computational social science

open access: yes, 2022
We discuss two computational approaches of particular significance for rigorous sociology, Agent-Based Computational Modeling (ABCM) and Computational Social Science (CSS). CSS exploits novel sources of large-scale data from, for example, the Internet, telephone-communication records, or population register data, studying digital traces of social ...
Flache, Andreas   +2 more
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Rodzicielstwo kobiet wychowujących dzieci w związkach jednopłciowych: struktura rodziny oraz lęk i unikanie przywiązaniowe a kompetencje rodzicielskie

open access: yesCzłowiek i Społeczeństwo
In the social sciences parenting of same-sex couples has been the subject of research since the 1970s, but in Poland there is still a lack of data on the subject.
Jowita Wycisk
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Rigor, Transparency, and Reporting Social Science Research [PDF]

open access: yesResearch on Social Work Practice, 2015
Dissemination of research is the most challenging aspect of building the evidence base. Despite peer review, evidence suggests that a substantial proportion of papers leave out details that are necessary to judge bias, consider replication, or initiate meta-analyses and systematic reviews.
openaire   +3 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Los Angeles County Social Survey, 1996 (LACSS)

open access: yes, 1996
The Los Angeles County Social Survey (LACSS) continues the Los Angeles Metropolitan Area Studies (LAMAS) and the Southern California Social Surveys (SCSS).
University of California, Los Angeles. Institute for Social Science Research.
core   +1 more source

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