Results 1 to 10 of about 2,524,397 (315)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Problemy Zarządzania, 2014 The aim of this paper is to analyze a perception of employer and employee social role (Goffman, 1959) by diverse social groups (Kostera, 2012) and its consequences for the psychological contract which is a significant relationship factor in working ...
Anna Pawłowska, Agnieszka Postuła
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Університети і лідерствоToday, the issue of cooperation and involvement of universities in solving social problems of communities is a strategically important task, and Ukrainian universities should take on the role of leaders of change and socio-economic development.
Nadiia Vasynova
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Student’s Attitudes to Parenthood and the Social Roles of Men and Women
Социологическая наука и социальная практика, 2019 The article analyzes the attitudes of young men and women based on a study of 1408 undergraduates of specialists in various fields of training at the age of 20–24 years, which held at the end of 2018 in Moscow and Stavropol.
Tatiana A. Gurko
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
SOCIAL CONFLICTS IN CHARITIES: REASONS, CONSEQUENCE SAND WAYS OF SOLVING THEM
Вестник университета, 2017 The article deals with the origin of social conflicts of international charities by addressing to a science of conflictology, it also emphasizes the difference between egoism and altruism related motivation of the parties involved into a charity process;
O. Andrienko
doaj
Diabetes in the city: the social role of dentists in fighting disease / Диабет в городе: социальная роль врачей-стоматологов в борьбе с болезнью [PDF]
Социология города, 2014 Currently in urban centers pandemic of diabetes is observed, which indirectly contributes to stressful rush of the city life. The article explores the role of a dentist as the first specialist able to suspect diabetes and motivate the patient to be ...
Maslak Elena Efimovna / Маслак Елена Ефимовна +2 more
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