Results 41 to 50 of about 11,191,782 (263)
, 2017 Across the medical and social sciences, new discussions about replication have led to transformations in research practice. Sociologists, however, have been largely absent from these discussions.
J. Freese, David Peterson
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FEBS Letters, EarlyView.This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause +2 more
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Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
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How Far Can We Go Through Social System?: Algorithmic Information Social Theories [PDF]
arXiv, 2005 The paper elaborates an endeavor on applying the algorithmic information-theoretic computational complexity to meta-social-sciences. It is motivated by the effort on seeking the impact of the well-known incompleteness theorem to the scientific methodology approaching social phenomena. The paper uses the binary string as the model of social phenomena to
arxiv
Computational Social Science: Discovery and Prediction
Analytical Methods for Social Research, 2016 Preface Gary King Introduction R. Michael Alvarez Part I. Computation Social Science Tools: 1. The application of big data in surveys to the study of public opinion, elections, and representation Christopher Warshaw 2.
R. M. Alvarez
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FEBS Letters, EarlyView.The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva +1 more
wiley +1 more source
Social Media as Windows on the Social Life of the Mind [PDF]
arXiv, 2007 This is a programmatic paper, marking out two directions in which the study of social media can contribute to broader problems of social science: understanding cultural evolution and understanding collective cognition. Under the first heading, I discuss some difficulties with the usual, adaptationist explanations of cultural phenomena, alternative ...
arxiv
The Acceptable R-Square in Empirical Modelling for Social Science Research
Social Science Research Network, 2022 Peterson K. Ozili
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Science Advances, 2015 Pluralism drawing on core social scientific concepts would facilitate integrated sustainability research. Resilience is often promoted as a boundary concept to integrate the social and natural dimensions of sustainability.
Lennart Olsson +4 more
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Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source