Results 41 to 50 of about 1,452,566 (223)
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Social Dynamics of Science [PDF]
Sci. Rep. 3:1069, 2013, 2012 The birth and decline of disciplines are critical to science and society. However, no quantitative model to date allows us to validate competing theories of whether the emergence of scientific disciplines drives or follows the formation of social communities of scholars. Here we propose an agent-based model based on a \emph{social dynamics of science,}
arxiv +1 more source
Conservation Science and Practice, 2021 Understanding coexistence between humans and threatened wildlife is a central focus in conservation. Way Kambas National Park in Sumatra Island, Indonesia, harbors one of the largest populations of the critically endangered Sumatran elephant (Elephas ...
Ardiantiono +7 more
doaj +1 more source
The Implementation of Character Education Based on Bugis Local Wisdom in Social Science Subjects
Al-Musannif, 2022 This study aims to analyze three sub-problems, namely (1) the implementation of Bugis local wisdom-based character education in social studies subjects, (2) the role of Bugis local wisdom values in shaping student character in social studies subjects ...
Anzar Abdullah +2 more
doaj +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
An Error-Correction Model for Information Transmissions of Social Networks [PDF]
arXiv, 2023 We study the error-correction problem of the communication between two vertices in a social network. By applying the concepts of coding theory into the Social Network Analysis (SNA), we develop the code social network model, which can offer an efficient way to ensure the correctness of the message transmission within the social netwoks.
arxiv
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source
Artificiality in Social Sciences [PDF]
Rennard, J.-P., Artificiality in Social Sciences, in Rennard,
J.-P. (Ed.), Handbook of Research on Nature Inspired Computing for Economics
and Management, p.1-15, IGR, 2006, 2007 This text provides with an introduction to the modern approach of artificiality and simulation in social sciences. It presents the relationship between complexity and artificiality, before introducing the field of artificial societies which greatly benefited from the computer power fast increase, gifting social sciences with formalization and ...
arxiv
Journal of Islamic Thought and Civilization, 2023 Significant efforts are made to revive scientific thinking,to require coordination through the application of the holistic elements of al-Qur’ān's scientific thinking.
Selamat Amir +2 more
doaj