Results 71 to 80 of about 16,775,741 (374)
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Science is not a Social Opinion [PDF]
Dentistry Journal, 2019 Recently, the main American associations in the dental field reported concerns regarding a film on the Netflix, Amazon, Apple, and Vimeo platforms that reported that endodontic treatments of root canals are linked to serious systemic pathologies, against any scientific evidence.
openaire +5 more sources
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Patent citation data in social science research: Overview and best practices
J. Assoc. Inf. Sci. Technol., 2016 The last 2 decades have witnessed a dramatic increase in the use of patent citation data in social science research. Facilitated by digitization of the patent data and increasing computing power, a community of practice has grown up that has developed ...
A. Jaffe, Gaétan de Rassenfosse
semanticscholar +1 more source
Editorial: A conversation about performative social science [PDF]
, 2008 Conversing by e-mail and mediated by an imaginary cyber-moderator, two of the co-editors of this Special Issue on Performative Social Science (PSS) Mary GERGEN and Kip JONES, themselves pioneers of PSS, engage in conversation around such topics as ...
Gergen, Mary, Jones, Kip
core +1 more source
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
InterAlia, 2016 In the article I critically examine my own research process based on unstructured interviews concerning the interviewees' lives as women. Inspired by feminist methodology and, above all, by queer theory, I reassess my prior resolutions.
Monika Kłosowska
doaj +1 more source
Analyzing Objective and Subjective Data in Social Sciences: Implications for Smart Cities
IEEE Access, 2019 The ease of deployment of digital technologies and the Internet of Things gives us the opportunity to carry out large-scale social studies and to collect vast amounts of data from our cities.
Laura Erhan +7 more
doaj +1 more source
Developing an e-infrastructure for social science [PDF]
, 2007 We outline the aims and progress to date of the National Centre for e-Social Science e-Infrastructure project. We examine the challenges faced by the project, namely in ensuring outputs are appropriate to social scientists, managing the transition from
Allan, Rob +17 more
core
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source