Results 71 to 80 of about 1,368,434 (261)
SOSYAL BİLİMLERDE META-METODOLOJİK BİR UNSUR OLARAK ZAMAN
Akademik İncelemeler Dergisi, 2018 Sosyal bilimsel yaklaşımlar önemli ölçüde kültürelayrımlara ve varsayımlara, kültürel ayrımlar ise örtük bir zaman tasavvurunabağlıdır. Kültürün bir bileşeni olan zaman, gerçekliğin toplumsal ve tarihselinşası sürecine dahildir.
Yılmaz Yıldırım, Muhammet Ertoy
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Science and Social Media [PDF]
Stem Cells Translational Medicine, 2019 Summary He Jiankui et al. conducted an experiment that resulted in the birth of the first human babies with germline gene editing. Initial and predominant communications of their work occurred via social media and outside of the norms for reviewing, approving, and engaging around work in science.
openaire +3 more sources
EXTENT OF ADOPTION OF VARIOUS ANIMAL HUSBANDRY PRACTICES AMONG THE LIVESTOCK REARING TRIBAL IN NORTHERN KERALA, INDIA [PDF]
Journal of Veterinary and Animal Sciences, 2017 The study was conducted with tribal from three districts viz , Wayanad, Kannur and Kozhikode . Data were collected using a structured intetrview schedule. The respondents were classified as livestock rearing and non livestock rearing.
T.S. Rajeev, T.T. Ranganathan
doaj
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Paul Delnooz (2025) Research Done Right
GiLE Journal of Skills DevelopmentBook ...
Brigitta Czók
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source