Results 101 to 110 of about 1,091,785 (170)

Editorial: Loneliness among youth and young adults. [PDF]

Front Psychiatry
Hemberg J, Schmidt R, Horigian V.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Understanding Multi-Victimization: Identifying Socioecological Supports Among Adolescents. [PDF]

J Sch Health
Smith EK, Gartner RE, Sterzing PR, Coulter RWS.   +3 more
europepmc   +1 more source

Youth awareness on death and dying in school settings: A scoping review on knowledge and practices. [PDF]

Palliat Care Soc Pract
Allard E, Coupat C, Létourneau D, Fortin G, Nguyen O, Lessard S.   +5 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Work-related musculoskeletal disorders and contributing factors among social security workers in Dar es Salaam: a cross-sectional study. [PDF]

Front Public Health
Lwaho S, Protas E, Asenga ED, Chombo S, Chilipweli PM, Mwelange L, Nyarubeli I.   +6 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Scrolling for science: Assessing the quality and accuracy of Crohn's disease-related content on Instagram reels. [PDF]

PLoS One
Madabhushi S, Patel A, Tse-Kang S, Liu A, Amin D, Rupawala A.   +5 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The Role of Illness Perception, Hope, and Perceived Social Support in the Prediction of Loneliness in Patients With Acute Coronary Syndrome: A Cross-Sectional Study. [PDF]

Health Sci Rep
Tehranineshat B, Faraghi A, Pasyar N, Rambod M.   +3 more
europepmc   +1 more source