Elevating Circulating L‐Kynurenine Promotes Frailty in Aging Mice
ABSTRACT Background L‐Kynurenine (L‐Kyn), a product of tryptophan catabolism, increases with age and has been associated with reduced physical function and increased frailty in humans. Robustly expressed in skeletal muscle, kynurenine aminotransferases (KATs) degrade L‐Kyn into kynurenic acid and are regulated by the transcriptional co‐regulator ...
Mia Y. Kawaida +8 more
wiley +1 more source
Longitudinal trends in vaping, smoking, and harmful alcohol use across sexual orientations in the UK (2014-2021). [PDF]
Bai Y +5 more
europepmc +1 more source
Role of Acid‐Sensing Ion Channels 1a in the Regulation of Obesity and the Gut Microbiota
ABSTRACT Objective Acid‐sensing ion channels are proton‐activated ion channels predominantly found in the nervous system. They are well known to affect metabolic and neurological health, yet their role in obesity and gut physiology remains unclear. This study investigates how systemic deletion of Asic1a influences obesity, metabolic, and gut‐based ...
Jane Shearer +7 more
wiley +1 more source
Short-Term Effects of a Structured Boxing Program on Technical Skill Acquisition in Novice Female Students. [PDF]
Martusciello F +5 more
europepmc +1 more source
Beliefs and Behaviors Related to Physical Activity in Black Girls With Asthma
ABSTRACT Introduction and Objective Physical activity (PA) is associated with improved asthma outcomes. Black girls face higher rates of asthma morbidity and are less likely to meet recommended PA than their White and Black male peers. To address these health disparities, it is essential to understand beliefs and behaviors related to PA among Black ...
Nora Spadoni +6 more
wiley +1 more source
Editorial: Coaching female athletes. [PDF]
Bahdur K, Nemčić Bojić T, Carson F.
europepmc +1 more source
Frequency Band Analysis of Multiple Stationary Time Series
ABSTRACT The frequency‐domain properties of biomedical signals offer valuable insights into health and functioning of underlying physiological systems. The power spectrum, which characterizes these properties, is often summarized by partitioning frequencies into standard bands and averaging power within bands.
Connor K. Brubaker +3 more
wiley +1 more source
Evaluating the impact of a national brain health education course for older adults with intellectual and developmental disabilities and caregivers: Brain Health-IDD Program protocol. [PDF]
Lunsky Y +25 more
europepmc +1 more source
Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary Aging
Mouse models revealed age‐associated increased circumferential stiffness of the proximal pulmonary artery that was associated with reorientation of collagen and decreased function of the lung and right ventricle. Age‐related transcriptional changes were indicative of senescence, ECM turnover, TGFβ signaling, and altered intercellular signaling among ...
Ruben De Man +22 more
wiley +1 more source
Physical activity promotion in Quebec primary schools: equity, intervention practices, and areas for improvement. [PDF]
O'Loughlin EK +5 more
europepmc +1 more source

