Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Differences in e-cigarette use, dependence, and knowledge between health and social sciences university students in Costa Rica. [PDF]
Solano-Maroto N +6 more
europepmc +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Health and Humanities and Social Sciences Professionals' Perceptions Regarding the Teaching of the Effects of Racism in Medicine: Semistructured Interview Study. [PDF]
Lambert M +4 more
europepmc +1 more source
Thermodynamics 2.0: Bridging the natural and social sciences. [PDF]
Poudel R +5 more
europepmc +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
The Impact of "Ethics Creep" on Research, Teaching and Learning in the Social Sciences and Humanities: A Survey of Canadian Researchers' Experience with Research Ethics Boards. [PDF]
Gallagher-Mackay K +2 more
europepmc +1 more source
Initial adaptation among university student: The case of the social sciences. [PDF]
Corti F +3 more
europepmc +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
A Nationwide Social Contact Survey Dataset for Public Health and Social Sciences Research in South Korea. [PDF]
Chae MK +5 more
europepmc +1 more source

