Results 211 to 220 of about 6,022,409 (321)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Methods matter: Exploring how expectations influence common actions

iScience
Summary: Behavior in controlled laboratory studies is not always representative of what people do in daily life. This has prompted a recent shift toward conducting studies in natural settings.
Andrea Ghiani, David Mann, Eli Brenner
doaj  

The BSSO Foundry: A community of practice for ontologies in the behavioural and social sciences. [PDF]

Wellcome Open Res
Hastings J, Zhang L, Schenk P, West R, Gehrke B, Hogan WR, Chorpita B, Johnston M, Marques MM, Webb TL, Baird HM, Crombez G, Michie S.   +12 more
europepmc   +1 more source

ECRIN - CESSDA strategies for cross metadata mappings in selected areas between life sciences and social sciences and humanities. [PDF]

Open Res Eur, 2023
Ohmann C, Moilanen K, Kleemola M, Canham S, Panagiotopoulou M.   +4 more
europepmc   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Assessing the impact of armed conflict on the progress of achieving 17 sustainable development goals

iScience
Summary: With global armed conflicts reaching a 30-year high in 2023, understanding their impact on the progress of Sustainable Development Goals (SDGs) is crucial.
Di Wang, Mengmeng Hao, Ning Li, Dong Jiang   +3 more
doaj  

Measuring transparency in the social sciences: political science and international relations. [PDF]

R Soc Open Sci
Scoggins B, Robertson MP.
europepmc   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Cooperation and competition have same benefits but different costs

iScience
Summary: Cooperation and competition shape everyday human interactions and impact individuals’ chances of success in different domains. Using a virtual Stroop test, classically employed to assess general cognitive interference, we examined the impact of ...
Lucia De Francesco, Alessandro Mazza, Matilde Sorrenti, Virginia Murino, Edoardo Battegazzorre, Francesco Strada, Andrea G. Bottino, Olga Dal Monte   +7 more
doaj  

Training and Technology Acceptance of ChatGPT in University Students of Social Sciences: A Netcoincidental Analysis. [PDF]

Behav Sci (Basel)
García-Alonso EM, León-Mejía AC, Sánchez-Cabrero R, Guzmán-Ordaz R.   +3 more
europepmc   +1 more source