Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel+9 more
wiley +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Correction: The abnormal audiovisual conflict in Parkinson's disease patients is manifestedin perception rather than response. [PDF]
Zhou H+6 more
europepmc +1 more source
Social roles and status of political science as general college education
Jae Woo Hong, Sungdai Cho, Soon Cheol An
openalex +1 more source
Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley +1 more source
Association between weight-bearing ankle dorsiflexion range of motion during deep squat sitting and quality of life after ankle fracture surgery: a cross-sectional study. [PDF]
Miyasaka H+5 more
europepmc +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Italian cross-cultural adaptation of the EveryONE Social Needs Screening Tool of social determinants of health in primary care. [PDF]
Campedelli L+11 more
europepmc +1 more source
Stochastic network modeling as generative social science
Steglich, Christian, Snijders, Tom
openaire +2 more sources