Results 291 to 300 of about 5,003,723 (357)

Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats

Advanced Biology, EarlyView.
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang, Biying Dong, Jie Chen, Zhenqiang Zhang, Weitong Zeng, Longxiong Liao, Xia Xiong, Xuejun Qin, Xianming Fan   +8 more
wiley   +1 more source

The impact of historical redlining policies on community composition and the COVID-19 pandemic in Boston. [PDF]

PLoS One
Alkhouri NB, Fisher V, Michel I, O'Connor C, Abuelezam NN.   +4 more
europepmc   +1 more source

Modelling Atherosclerotic Plaque Cap Mechanics: Microcalcifications Reduce Mechanical Properties in Mesenchymal Stromal Cell‐Based Model

Advanced Biology, EarlyView.
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen, Deniz Şahin, Frank J.H. Gijsen, Eric Farrell, Kim van der Heiden   +4 more
wiley   +1 more source

Antihypertensive medication adherence and associated factors among adult hypertensive patients at public hospitals in eastern Ethiopia: A Cross-sectional study. [PDF]

PLoS One
Yousuf J, Roba KT, Ahmed N, Belsty T, Wondimneh F, Daba L, Teshager T, Ketema I.   +7 more
europepmc   +1 more source

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

Evaluation of the social and economic impact of extreme weather events in people living with HIV in KwaZulu-Natal, South Africa (S3E project): Protocol for a mixed-method study. [PDF]

PLoS One
Babashahi S, Orievulu K, Eyita-Okon E, Kniveton D, Iwuji C.   +4 more
europepmc   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Depressive and anxiety symptoms, and their associated factors among adult, visually impaired follow-up patients attending the Hawassa University Comprehensive Specialized Hospital Eye Care and Training Center, South Ethiopia, 2024. [PDF]

PLoS One
Wube BF, Addis Y, Alemayehu BF, Etsub SA, Eticha BL.   +4 more
europepmc   +1 more source

Patient-informed outpatient intervention to improve pregnancy outcomes through connections to social services: protocol for the BETTER randomised controlled trial. [PDF]

BMJ Open
McAlearney AS, MacEwan SR, Huerta TR, Thomas NR, Sova LN, Roth L, Bartholomew A, Rush LJ, Johnson KF, Grobman WA.   +9 more
europepmc   +1 more source

Retention in HIV Pre-Exposure Prophylaxis Among Men Who Have Sex with Men in Tanga, Tanzania. [PDF]

HIV AIDS (Auckl)
Kiondo F, Metta E, Mmbaga EJ, Leshabari MT, Swai C, Mbotwa CH, Moen K.   +6 more
europepmc   +1 more source