Results 31 to 40 of about 330,278 (308)

Intraperitoneal metastases from cutaneous melanoma in a 2-year-old girl: A case report

open access: yesJournal of Pediatric Surgery Case Reports
Introduction: Cutaneous melanoma represents less than 1 % of all pediatric malignancies, with an incidence of 4.9 cases per million in children aged 0–4 years. Intraperitoneal metastasis is exceptionally rare in this population.
García-Ledezma Arnold   +5 more
doaj   +1 more source

Rapidly progressive glomerulonephritis and ANCA-negative pauci-immune vasculitis: an unusual presentation. A case report

open access: yesPočki, 2023
Rapidly progressive glomerulonephritis corresponds to a clinical scenario of glomerular damage involving rapid deterioration of renal function with multiple etiologies.
Zitlali Guadalupe Paulín Zepeda   +4 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Pregnancies with Platelet Count Lower Than 70000 Platelets/μl

open access: yesGynecology Obstetrics & Reproductive Medicine, 2006
OBJECTIVE: In this study, pregnancies complicated with thrombocytopenia platelet count lower than 70000 platelets/μl were ev aluated. STUDY DESIGN: Twenty two pregnancies with platelet count lower than 70000 platelets/μl were ev aluated according to age,
Semih Mun   +5 more
doaj  

Embryonal carcinoma metastasis from pure testicular teratoma mimicking a complex renal cyst

open access: yesUrology Case Reports, 2021
Teratoma is frequently found in mixed germ cell testicular tumors in up to 80% of cases, but as a pure component it is reported in only 2–6% of cases. Metastatic disease may be seen in 29–76% of these cases in the adult population. We present the case of
Martínez Garfias Arturo Enrique   +4 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

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