Results 81 to 90 of about 794,843 (261)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Can the morality of a group whose members are interdependent be extended to all humanity and beyond?

open access: yesEvolution: Education and Outreach, 2019
I review David Sloan Wilson’s This View of Life, which considers why a group’s members, if tightly interdependent, must treat each other sympathetically, justly and generously, and what actions could cause these sentiments to extend to all humanity.
Egbert Giles Leigh
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Aspect Selection for Social Recommender Systems

open access: yes, 2015
This research has been partially supported by AGAUR Scholarship (2013FI-B 00034) and NASAID (CSIC Intramural 201550E022).
Yoke Yie Chen   +3 more
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Behavior Selection of Stakeholders toward Megaproject Social Responsibility: Perspective from Social Action Theory

open access: yesAdvances in Civil Engineering, 2019
The importance of social responsibility strategy for the sustainable development of megaprojects has been widely concerned, while types and motivations of social responsibility behavior have also been analyzed and examined in the corporate management ...
Linlin Xie, Ting Han, Haitao Chu, Bo Xia
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Selection material for social cultural competence formation

open access: yesPolylinguality and Transcultural Practices, 2010
In this article author offers main criteria of material selection for social cultural сompetence formation and analyses the text as the principal source of linguistic cultural information.
Y V Yemeljanova
doaj  

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