Results 111 to 120 of about 394,263 (258)

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

open access: yesAdvanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol   +16 more
wiley   +1 more source

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

open access: yesAdvanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye   +11 more
wiley   +1 more source

Programmable Microgel Degradation in Dynamic Granular Hydrogels Guides Extracellular Matrix Assembly During Tissue Repair

open access: yesAdvanced Materials, EarlyView.
This study reports on the chemical modification of hyaluronic acid to create hydrogels with hydrolytic degradability ranging from 2–28 days. Granular hydrogels that undergo timed degradation to increase porosity enhance cell invasion and provisional ECM remodeling in a muscle injury model, leading to reduced fibrosis and improved regeneration ...
Zhiyuan Chen   +7 more
wiley   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

open access: yesAdvanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren   +6 more
wiley   +1 more source

Amphiphilic Non‐Isocyanate Polyurethane Coatings With Tunable Antifouling and Fouling‐Release Performance: A Log‐Ratio Assessment Framework

open access: yesAdvanced Materials Interfaces, EarlyView.
Amphiphilic non‐isocyanate polyurethane (NIPU) coatings containing reactive hydrophobic poly(dimethylsiloxane) (PDMS) and hydrophilic methoxy poly(ethylene glycol) (MPEG) prepolymers for marine antifouling (AF) and fouling‐release (FR) applications were investigated. The coatings were evaluated with a set of representative marine foulants.
Nastaran Shahzadeh   +7 more
wiley   +1 more source

Impact of social support and self-efficacy on functioning in depressed older adults with chronic obstructive pulmonary disease

open access: yesInternational Journal of COPD, 2008
Patricia Marino, Jo Anne Sirey, Patrick J Raue, George S AlexopoulosDepartment of Psychiatry, Weill Medical College of Cornell University, White Plains, NY, USAObjective: The objective of this study was to examine the association between social support ...
Patricia Marino   +3 more
doaj  

Metal Compound‐Based Non‐Enzymatic Electrochemical Cholesterol Sensors: Emerging Materials and Mechanistic Insights

open access: yesAdvanced Materials Interfaces, EarlyView.
This review discusses recent progress in metal complex‐based, non‐enzymatic electrochemical sensors for cholesterol detection. We examine metal oxides, metal sulfides, and hybrid nanomaterials, highlighting their catalytic mechanisms and material design strategies.
Longfei (Jack) Yin   +6 more
wiley   +1 more source

A Self‐Cleaning Solar Evaporator Based on MXene/Aramid Nanofiber Aerogels for Efficient Water Desalination

open access: yesAdvanced Materials Interfaces, EarlyView.
This study develops a self‐cleaning solar evaporator based on MXene‐coated aramid nanofiber aerogels for efficient desalination under high‐salinity conditions. The cylindrical evaporator combines strong photothermal conversion, capillary water transport, and self‐rotation triggered by salt accumulation.
Mandeep Singh   +5 more
wiley   +1 more source

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

open access: yesAdvanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani   +2 more
wiley   +1 more source

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