Results 91 to 100 of about 5,221,339 (294)

Valuing service design: Lessons from SROI [PDF]

, 2012
This paper describes lessons learned through the use of a Social Return On Investment (SROI) approach to evaluate a completed Service Design project with a large vocational training company.
Lievesley, Matthew, Yee, Joyce
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

USER INVOLVEMENT IN POVERTY POLICY STRUCTURES AS AN APPROACH TO GIVE A VOICE TO PEOPLE LIVING IN POVERTY AND TO STRENGTHEN SOCIAL COEHISION

Banber Erevani Hamalsarani. Sots'iologia
Solidarity and social inclusion, which are often used as synonyms in professional discourse on social work, are understood to date with too little focus on the structural level in politics, economics and social services.
Emanuela Chiapparini
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

KONTRIBUSI HIMABIWA DALAM PENGABDIAN KEPADA MASYARAKAT MELALUI BAKTI SOSIAL DI KALURAHAN BANYURADEN

Abdimas Altruis
Community service activities play a crucial role in fostering social awareness and student engagement in improving community welfare. This community service activity promoted the contribution of students in enhancing community welfare through a food ...
Antonius Satria Hadi, Utami Tunjung Sari, Bhenu Artha, Bahri Bahri, Niken Permata Sari, Cahya Purnama Asri, Ardi Ardi   +6 more
doaj   +1 more source

Including Social Service Clients in the Organizational Decision Making Process [PDF]

, 2012
Empowerment of clients is a goal of many social service organizations and yet a concept that is hard to define and often complicated to implement. This professional project looks at the importance and practice of empowering parents in a teenage pregnancy
de Hartog, Josie
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

PERFIL DO CORPO DOCENTE, TUTORIAL E DE COORDENAÇÕES DE CURSOS DE SERVIÇO SOCIAL NA MODALIDADE DE EAD

Revista de Políticas Públicas, 2012
The article notes the growth of the sport of distance education in higher education, as a strategy of expansion of higher education in Brazil, without the respective state investment. Under the Social Service, the phenomenon of growth of this modality of
Larissa Dahmer Pereira
doaj